Citescore values are based on citation counts in a given year e. Journal finder download the understanding the publishing process pdf. Structural study of the influenza a virus rnadependent rna polymerase. It was established in 1958, from the former beijing experimental biology institute founded in 1957. Different signals, including hormones, inflammatory cytokines and metabolic signals, work in a collaborative way to regulate contextspecific gene programs in normal growth and. These eleven faculty members and their labs are housed in the kasha laboratory building at the institute of molecular biophysics. We thank zhijie liu and neil shaw institute of biophysics, chinese academy of sciences for advice on protein purification, jindong zhao institute of hydrobiology, chinese academy of sciences, and peking university for suggestions on protein analysis, takamure itsuro hokkaido university for providing d27 and d10 mutants, and dun li stony. Sun,9 yunpeng song,9 liaoyuan hu,9 zhijie liu,1,2 raymond c. Archives of biochemistry and biophysics editorial board. Lingpeng cheng institute of biophysics, chinese academy of sciences verified email at moon. Structure of rnadependent rna polymerase from 2019ncov, a.
The harvard biophysics graduate program phd research at the interface of quantitative science and biology. National laboratory of biomacromolecules, institute of biophysics, academia sinica, beijing 100101, peoples republic of china. Zhijie liu chinese academy of sciences, beijing researchgate. Shanghai institute of applied physics shanghai synchrotron. I am equally proud to be working with the biophysical society of china, and biophysics reports is the societys official journal. Zhijie jason liu assistant professor university of. Zhijie liuinstitute of biophysics chinese academy of. Yan gao, view orcid profile liming yan, yucen huang, fengjiang liu, yao zhao, lin cao, tao wang, qianqian sun, zhenhua ming, lianqi zhang, ji ge, litao zheng, ying zhang, haofeng wang, yan zhu, chen zhu, tianyu hu, tian hua, bing zhang, xiuna yang, jun li, haitao yang, zhijie liu, wenqing xu, luke w. Enhancer activation requires transrecruitment of a mega transcription factor complex. Structure of rnadependent rna polymerase from 2019ncov, a major antiviral drug target. Guddat6, quan wang2, zhiyong lou1, zihe rao1,2,3,7.
Institute of biophysics, chinese academy of science linkedin. Qianqian sun,1 cenfeng chu,1,2,4 jie yang,1,2,4 liu yang,1,2,4 quan wang,1, 2,4. Mmpl3 has emerged as an important target for antituberculosis drug discovery with inhibitors of this protein currently in clinical trials. Crystal structures of membrane transporter mmpl3, an antitb. A draft sequence of the rice genome oryza sativa l. Rapid development of an inactivated vaccine for sarscov2. Professor shizhang bei, a renowned biologist and a distinguished cas member, founded the institute in 1958. Herein, a singleatom dispersed ag loaded ultrathin gc3n4 hybrid agtcmucn was prepared through a facile copolymerization of dicyandiamide w. The covid19 pandemic caused by sarscov2 has brought about an unprecedented crisis, taking a heavy toll on human health, lives as well as the global economy. Genomics institute, school of plant sciences and department of ecology and evolutionary biology, bio5 institute for collaborative research, university of arizona, tucson, az 85721, usa. Shao, baodong liu, yong zheng, hailin wang, xiaoguang lei, zhuqiang zhang, bing zhu presenter affiliation.
Dwarf27, an ironcontaining protein required for the. It was established by bei shizhang in 1958, from the former beijing experimental biology institute founded in 1957. Institute of biophysics, chinese academy of sciences, beijing, china. National institute of biological sciences, beijing, china. Theory of free energy and entropy in noncovalent binding. View zhijie jason liu s profile on linkedin, the worlds largest professional community. The true understanding of its role in host defense responses has been hampered by numerous reports of comparable systems with contradictory interpretations of crp as a stimulator, suppressor, or benign contributor to such processes. Selfcapping of nucleoprotein filaments protects the newcastle. The precise function of creactive protein crp as a regulator of inflammation in health and disease continues to evolve. Covid19 virus is reported to be a new member of the betacoronavirus genus and is closely related to severe acute respiratory syndrome coronavirus sarscov and to several bat coronaviruses. Zhanga 6 a national laboratory of macromolecules, institute of biophysics, chinese academy of sciences, 15 datun road, beijing 100101, china 7 bkey laboratory for cell proliferation and regulation biology of the ministry of education, institute of cell biology, beijing normal university.
Department of physics and institute of molecular biophysics, florida state university, tallahassee, florida 32306, and center for advanced research in biotechnology, university of maryland biotechnology institute, rockville, maryland 20850. An efficient strategy for high throughput screening of. Apr 10, 2020 corona virus disease 2019 covid19 caused by a novel coronavirus emerged in december 2019 and has since become a global pandemic. The institute of biophysics, chinese academy of sciences, based in beijing, china, focuses on biophysically oriented basic research in the life sciences. For each target protein, every pair of residues was treated as potential disulfide bond candidate. Bing zhang, xiuna yang, jun li, haitao yang, zhijie liu, wenqing xu, luke w. Guangzhou institute of biomedicine and health, chinese academy. Sheep and goats in northwest china suffer from theileriosis from infection with theileria sp. Institute of biophysics, chinese academy of sciences ibp, cas welcome message dear colleagues, on behalf of the organizing committee, it is our great pleasure and privilege to invite you to participate in the 17th international biophysics congress ibc iupab, which will be held in beijing from oct.
Sanzhen liu,3 zhijie liu,6 dawn holligan nagel,17 maureen c. Yanxin liu university of california, san francisco verified email at msg. Migration of point defects and a defect pair in zinc oxide using the dimer method volume 27 issue 17 dong chen, fei gao, mingdong dong, bo liu. Xiaodong sun, head of ophthalmology, professor and vice dean, shanghai general hospital. Hence, rapid development of effective vaccines against sarscov2 is urgently needed. In order to test our prediction program, two proteins, bril and flavodoxin, were used as examples for disulfide bond engineering. Here, crystal structures of mycobacterial mmpl3 alone and in complex with four tb drug candidates have been determined. Structure of the rnadependent rna polymerase from covid19. Structure of rnadependent rna polymerase from 2019ncov.
The facile synthesis of a single atomdispersed silver. Zhijie liu chinese academy of sciences, beijing cas. The chinese biophysics congress is the largest and leading academic event in the domestic field of biophysical sciences. Migration of point defects and a defect pair in zinc oxide. The use of phageassisted continuous evolution pace with both positive and negative selection enables the rapid development of orthogonal aminoacyltrna. With biophysics reports, we will provide a resource on novel theories, methods, protocols and improvements on basic research techniques in the biological and biomedical sciences. Song liu,1 jian yang,1 guangyu zhang,1 yuqing xiong,1 zhijie li,1. Journal of molecular cell biology, volume 11, issue 12, december 2019, pages 11011103.
Li2, haitao yang2, zhijie liu2, wenqing xu2, luke w. Ning liuinstitute of biophysics chinese academy of. Complexity, diversity, and dynamics this copy is for your personal, noncommercial use only. Liu, zhijie graduate school of biomedical sciences. This disambiguation page lists articles associated with the title institute of biophysics. Max planck institute of biophysics department of theoretical biophysics, frankfurt am main, germany theory and molecular simulation, protein. Oct 16, 2017 mengchen pu, zhijie xu, and yao peng have contributed equally to this work. The institute of biophysics, chinese academy of sciences cas, focuses on basic research in the life sciences. To investigate the immune response to infection with theil. Enabling the optimal usage of solar energy is considered to be one of the most pressing challenges in the photocatalytic remediation of water resident contaminants. Protein crystal quality oriented disulfide bond engineering ncbi.
The 16th chinese biophysics congress is scheduled to take place from aug 24 to 27 in chengdu, sichuan province, according to an announcement released by the biophysical society of china bsc on may 28. Institute, school of life science and technology ihuman institute. In this paper, the groups led by liu, shen and ouyang reports the first. Enhancer activation requires transrecruitment of a mega. Yan gao, liming yan, yucen huang, fengjiang liu, yao zhao, lin cao. Ning liuinstitute of biophysics chinese academy of sciences. Structural basis for termination of aim2mediated signaling by p202. Cd47 blockade triggers t cellmediated destruction of. Institute of biophysics and the university of chicago joint group for. View the profiles of professionals named zhijie liu on linkedin. Zhijie liu, yanxin wang, hongwei gao key laboratory of plant resources and chemistry in arid regions, xinjiang technical institute of physics and chemistry, chinese academy of. Protein crystal quality oriented disulfide bond engineering. Molecular mechanism for ligand recognition and subtype. The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of.
How many fold types of protein are there in nature. These data pave the way for the rational development of mmpl3 inhibitors as potent tb drugs. Find out more about the editorial board for journal of molecular biology. There are no sarscov2specific treatments or vaccines available due to the novelty of this virus. Institute of biophysics, chinese academy of sciences. Biophysics 4627 cancer biology 3626 cell biology 56 clinical trials 7 developmental biology 39. Zhijie liu, professor and executive director, ihuman institute, shanghaitech university. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
233 1542 205 409 635 292 444 1052 1023 81 1381 702 1058 1530 1262 647 1201 543 692 1343 92 1282 589 1356 1044 1014 177 790 580 372 897 940 1056 696 1227 1216 1188 1081 787 899 434